Royal Air Force Typhoon fighter aircraft have conducted a mission with French aircraft in a combined operation targeting an subterranean weapons facility in Syria employed by the IS group, per a report from the UK's MoD.
The facility, pinpointed through surveillance, was believed to be containing munitions and bombs, the statement said, and was situated in hills just above the historic site of Palmyra in central Syria.
"The RAF jets utilized Paveway IV guided bombs to hit a series of access tunnels providing entry to the depot... preliminary assessments suggest the strike was effective," the MoD said.
There was no sign of any civilian casualties in the operation on Saturday evening and all the aircraft made a safe return, the defence officials confirmed.
The Typhoon FGR4s were supported by a Voyager tanker plane.
Daesh - also known as ISIS - established jihadist rule over parts of Syria and Iraq before its territorial defeat in 2019.
"This operation underscores British leadership, and determination to operate in unison with our partners, to eradicate any resurgence of the terrorist group and their harmful and extremist ideologies in the area," the British Defence Secretary John Healey said.
RAF aircraft have performed overwatch operations over Syrian airspace to "prevent any attempted comeback" of the group following its routing at the climactic battle in Baghuz in 2019, the authorities noted.
"I want to thank every member of British forces participating in this operation for their professionalism and their bravery," he added. "They were part of thousands of British personnel stationed over Christmas and New Year. This action, to take out militants who pose a risk to our safety, shows how British military are ready to step up, continuously, keeping Britain secure within its borders and powerful internationally."
Last December, the United States armed forces executed what it termed a "major assault" targeting Daesh sites in Syria, following an ambush resulted in the deaths of two American soldiers and a local interpreter in Palmyra.
The United Nations estimates Islamic State still boasts an estimated 5,000 to 7,000 combatants in Syria and Iraq.